Quality Assessment of Medical Heparin Using Laser Scattering Technique

Abstract

In this work, the goodness of the medical Heparin (concentration) was checked using the principle of laser scattering. A simple setup consists of diode laser with wavelength 532 nm and output power of 100 mW and USB spectrometerwere used to record the laser scattered intensity at angles of (〖45〗^°,〖90〗^° and 〖135〗^°). First of all, the relation between the concentration of the standard sample (NaCl) and the scattered laser intensity in these angles was pointed. Then the relation between the heparin concentration and the intensity of the scattered laser light was deduced for the three angles. The results showed that the relation between the angular scattered intensity and the sample concentration is a linear relation. This study proved that this setup was sensitive and efficient indiscovering any change in the sample concentration and any manipulation in theconcentrationof Heparin, so the goodness of Heparin can be checked.