Abstract:
This Descriptive analytical Case control study, carried out to study the assessment
of von willebrand factor antigen level in aortic stenosis Sudanese patients
conducted at Ahmed Gasim hospital during the period from January 2017 to May
2017 at Khartoum state. the study include eighty samples forty as control and forty
were patients already diagnosed as Aortic stenosis 27 (68%)of them were male
and 13(33%) of them were female . 4.5 ml of venous blood was with drown from
each patient, placed in tri sodium citrate container then we separate the sample by
centrifuge and extract plasma to measure von willebrand factor antigen level by
using Enzyme Linked Immuno Sorbent Assay. the results was analyzed by
statistical package for social science computer program (SPSS) version 16.
The result showed that the mean VWF:Ag level was insignificant difference
between case study and control (p. value> 0.05).the mean of von willebrand factor
antigen level within case (0.735 ± 0.0174) and in control (0.713 ± 0.0212) .
While There was no statistically significant difference between the vWF: Ag
concentration and severity of disease (p.value>0.05) and there was no statistically
significant difference between the plasma vWF: Ag concentration and gender
(p.value>0.05).
