Assessment of Prothrombin time and Activated Partial Thromboplastin timeinDiabetes MellitusType 2 Patients in Khartoum State

Abstract

This is analytical case control study out in Khartoum state in International Hospital, during the period fromJune to November 2017 to evaluate some coagulation parameter in Sudanese patients with diabetes mellitus type2. 50 diagnosed diabetesmellitus type2 were enrolled cases and 50 healthy individuals were selected as control group with age more than 40 years ,4.8 ml venous blood was with drown from each group, placed in tri sodium citrate then centrifuge to get platelet poor plasma (ppp)and that to measure PT and APTTthe result was analyzed by Statistical Package for Social Sciences SPSS version 20, and expressed as means, STD, Pvalue. The results obtained from CONTROL that the means of prothrombin time, and activated partial thromboplastin time within the normal range but significant increase than the result in control group, in patients group (11.18±0.41sec), (31.88±2.20sec)respectively the means ofprothrombin time, and activated partial thromboplastin time in Patient group(9.54±0.58sec), (19.94±0.62sec)respectively (P.value< 0.001). There are no significant differences in both group of sex (P.value=0.064)