Study of the factors affects the five years survival rate of prostate cancer patient in Sudan

Abstract

Prostate cancer considers one of the furthermost tumors in world; it classify second among all cancers after breast cancer. It likewise the most common type among the Sudanese males.The five-year survival rate is the percentage of patients live five years after the disease is diagnosed used to evaluate the effectiveness of diagnosis and treatments. There are many methods to calculate the five-year survival rate in my thesis used direct method, observed, corrected and Relative survival rate.The aim of this study was to Study the factors affects the five year survival rate of prostate cancer in Sudan.This study was conducted in Sudan during the period from July 2013 to June 2016. One thousand, one hundred and seventy seven patients were included in the study; they were processed to determine the common age,Region, marital status, patient parents relative and incidence of all prostate cancer record in statistic office in RICK from January 2010 to December 2012.About three hundred and six patients were studied through 5 years in order to assess the status of survival.This study through direct method foundthat only 111 out of 306 (36.3%) patients were surviving 5 years after the date of first treatment. Estimation of the 5YSR of prostate cancer for patients age 45 to 97 years by observed, corrected and expected five survival of the population in respect to Kalban-Meier calculation methods , the study found that the survival rates were 39%, 42% and 44% (p> 0.05) respectively.This study found that there were many factors affected the survival rate in Sudan population such as age, treatment type, grade and site of metastases. In conclusion 5YSR can be estimated in Sudanese by using the following linear equation as indigenous formula: Survival rate =(-1.396 × Grade) + (0.19 × Treatment) + (-0.105 × Site of MITS) + 6.53