Assessment of the Serum Levels of Urate, Creatinine and Blood Haemoglobin A1c among Sudanese with Type 2 Diabetes Mellitus

Abstract

This is a cross- sectional study conducted in the military hospital in khartoum state during the period from Faberuary to Augest 2012. The aim of this study is to compare the serum levels of urate , creatinine and blood HbA1c % of 60 patients with type 2 diabetes as a test group and 40 apparently healthy subjects as a control group . Age and sex were for both the test group and the control group were matched. Serum urate , creatinine and blood HbA1c were determined using cobas integra 400 plus and kits from Rouch company . This study Shows a significant increase in the serum urate, creatinine and blood HbA1c% in type 2 diabetic patients compared with non diabetic subjects as control ( P ≤ 0.05 ). In addition a positive relationship was noticed between duration of the diabetes mellitus with both serum urate and the serum creatinine . Insignificant a weak positive relationship was observed between the serum levels of creatinine and the BMI .Where as no significant correlation was noticed between the BMI and the serum levels of urate .HbA1c% showed week positive relationship with the duration . Inconclusion; the serum levels of urate ,creatinine and blood Hb A1c% are increased in diabetic patients with type 2 diabetes mellitus.There is positive correlation between urate ,creatinine and blood Hb A1c % and the duration of diabetes mellitus. There is a weak relationship between the serum levels of creatinine and the BMI , and no correlation between the serum levels of urate and the BMI .