A Retrospective Study to Determine Infertile Sudanese Women with Hyperprolactinemia

Abstract

This study aimed to determine prevalence rate of Sudanese infertile women with hyperprolactinemia attended Reproductive Health Care Center. The selected period of the study started from 2005 to 2010. The data was obtained from the statistical records available in the center to determine the prevalence rate of target group .Prolactin, FSH and LH serum levels were determined using Enzyme Immunoassay Technique ( EIA). A total of 14129 infertile women attended the center during the study period, 4096 of them with hyperprolactinemia ( prolactin < 400 IU / L ) and a prevalence rate of 29% . Among the hyperprolactinemic subjects, 39.4% with FSH > 12.9 IU/ L and 12.2 % with LH > 9.6 IU/L Two groups were selected from hyperprolactinemic subjects. Group A which composed of 2333 (16.5% of total infertile women or 57% of hyperprolactinemic patients) were hyperprolactinemic with regular menstrual cycle . Group B which composed of 491 ( 3.5% of total infertile women or 12 % of hyperprolactinemic subjects ) amenorrhic hyperprolactinemic patients . In conclusion, high prevalence of infertile Sudanese women with hyperprolactinemia was observed . Prevalence of women with hyperprolactinemia associated with high FSH was more common compared to those with hyperprolactinemia and high LH. Higher prevalence of Infertile hyperprolactinemic women with regular menstrual cycle compared to infertile hyperprolactinemic women with a menorrhea was observed.