Preparation, characterization and biological activity of chromium phthalocyanine chloride complex

Abstract

This work presents the preparation, purification, identification and applications of chromium (III) phthalocyanine chloride complex. Non-solvent method was used for the preparation at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria