Assessment of Serum Levels of Urea ,Creatinine and Urate among Type II Diabetic Patients With Myocardial Infarction

Abstract

Across –sectional study conducted during the period from May 2012 to August 2012 to asses and compare the serum levels of urea ,creatinine and uric acid among type 2 diabetic patients with myocardial infarction . FortySudanese type 2 diabetics with myocardial infarction were selected as a test group from Sudan Heart Center ,Medical Modda Hospital ,Bolice Hospital and Alshab Hospital in Khartoum state , Sudan. The test group was compared with a control group(1), which included 30 apparently healthy volunteers and acontrol group (2)which included 30 sudanese with type 2 II diabetes mellitus without myocardial infarction from Specialized Zinnam Hospital . Age and gender of the test group were matched with the control groups. Blood specimens were collected from all participants in this study . Serum levels of urea ,creatinine and uric acid were measured using spectrophotometric methods . Statistical pakage for Social Science (SPSS version 11.5) computer software was used for data analysis. The results of this study indicated asignificantly raised means of the serum levels of urea ,creatinine and uric acid of the test group when compared with the control groups. Urea was significantly increased in the test group when compared with the healthy group (1) (p=0.00). Serum creatinine of the test group was significantly raised when compared with control group(1) ( p=0.29) . Serum Uric acid of the test group is also significantly raised compared with control group(1) (p=0.00). Serum Urea was significantly increased in the test group when compared with the control group (2) (p=0.00). Serum creatinine of the test group was significantly raised when compared with control group(2) ( p=0.00) . Serum Uric ‫‪acid of the test group is also significantly raised when‬‬ ‫.)00.0=‪compared with control group(2) (p‬‬ ‫‪In this study these is a significant correlation between the‬‬ ‫‪duration of diabetes of the test group and the serum levels‬‬ ‫. ‪of urea ,creatinine and uric acid mg/dl‬‬