Determination of Complete Blood Cell Count of Sudanese Pregnant Women during pregnancy attended in El Obeid Teaching Hospital

Abstract

This was a case control study, conducted in North Kordofan State at El Obied Teaching Hospital during the period from March to December 2016The study aimed to determine CBC ofSudanese pregnant women during pregnancy. There are 120 pregnant women (case) and 60 non pregnant women as matched age (controls). All subjects were informed verbally about the study and approved for participation. Two and half ml of venous blood was collected in EDTA anticoagulant container. Automated hematological analyzer (Mindary Bc-300 plus) was used.The results were analyzed by independent T test in the SPSS (version 16) computer program. Demographic results collected through questionnaire showed thatmost of study volunteer women were poor and live in rural areas, and the majority of them were illiterate and in third trimester 84/120 (70%). The aged women weredivided into age groups, age group (21-30) year was most frequent group in all subject 68/120 (56%) in pregnant women and30/60 (50%)in non-pregnant women.One third of pregnant women hada history of miscarriages, while multigravidae was most frequent 48/120 (40%) and secondary gravidia were least frequent 35/120 (29%).And only 27% of pregnant women have anemia, and most of them had mild anemia. Hb content, RBC and MCH of pregnant women were significantly decreased (p.value< 0.05) compared to non-pregnant women.There was statistical significant increase in WBC count and granulocyte (P.value< 0.05) in pregnant women compared to non-pregnant women, while HCT, MCV, MCHC showed insignificant decreased (p value > 0.05) in pregnant women compared to non- pregnant women. There was no statistical correlation in CBC parameter between first and second trimester, and in contrast to there was statistical significant correlation in CBC parameter between second and third trimester (P.value<0.05). Effected of different factor on CBC parameter showed that: history of miscarriageamong pregnant women may be effected means ofHb and platelet (p. value = 0.05), while had no affected on means of HCT, RBC and WBC (pvalue<0.05). Anemia was statistical correlation effected on means of Hb, HCT and RBC, while there was no statistical correlation effected on means ofWBC and Platelets. Number of pregnancies was significant effected on means of platelets (p. value > 0.05), while there were no affected on means of Hb, HCT, RBC and WBC. No significant effectedof Socioeconomic, Education and Residence on CBC parameter.