Evaluation of Diagnostic Performance of Computed Tomography in Diagnosis of Liver Diseases

Abstract

This study was prospective study done in Sudan during the period from February 2014 to January 2017 at Alfaisal Specialized Hospital, Ibn alhaitham Diagnostic Centre, Antalya Medical Centre and Royal Care International Hospital. The data were collected by using data collection sheet for 100 patients who were suspected to have liver disease. They have abdominal ultrasound (US) and abdominal computed tomography (CT) exam using triphasic scan protocol. There was high frequency of diffused and focal liver lesions in Sudanese patient therefore, diagnosing and characterization of these lesions is essential. The objectives of this study to characterize and diagnosis liver disease using multidetector computed tomography (MDCT) and evaluated the diagnostic performance of computed tomography (CT) and ultrasound (US( in diagnosing liver diseases. All the data obtained in the study were documented and analyzed using Statistical Package for the Social Sciences (SPSS) program to test the significance of differences, p-value of less than 0.05 was considered to be statistically significant. The study results were liver lesions were detected. The nature of the lesions was characterized in all phases of contrast. Enhancement patterns of benign disease, malignant and metastases were also been analyzed. Triphasic CT scan results showed that 13(26.0%),of the lesions were well enhanced ,19(38%)were intermediately enhanced where 18(36%) reflect no enhancement in the arterial phase. lesions that still enhanced in the delay phase were(9/50/18%)constituting hemangioma8(16%) and liver tumors 1(2%);where in the venous phase the enhanced lesions constituting 30(60%) and including lesions of liver metastases. Arterial and venous phase images are helpful in the detection of hyper vascular lesions and are essential for the characterization of a large proportion of lesions. Equilibrium phase images demonstrate benign focal liver lesions, and Triphasic liver (CT) enables characterization of a wide range of liver lesions and characterized them significantly at p≤0.000. Also the study revealed significant relation between the enhancement, character of the lesions and the sonographic findings with the CT diagnosis at p < .001 and p < .001 and p< 0.017 respectively. Contrast-enhanced CT improves the diagnostic performance in liver lesions compared with baseline sonography.