Abstract:
Diabetes mellitus is one of the most common metabolic diseases worldwide. This metabolic disorder contributes greatly to the significant proportion of the burden of renal damage and dysfunction.
The aim of the study was to investigate the renal function of the diabetic patients who reside in United Arab of Emirates, diagnosed as diabetes mellitus type -2.
A cross-sectional study conducted during the period from July 2015 to June 2016 to determine and to evaluate the plasma Creatinine and Uric acid in Sudanese resides in UAE. A total of hundred of subject were recruited in the study. Fiftywith type 2 diabetes mellitus were selected as a test group 96% is male and fifty healthy volunteers as a control group 98% are male. Demographic datadescripe age and gender as well as medical history were obtained through the administration of a questionnaire. Blood samples were collected and analyzed for glucose, HbA1c, uric acid, and creatinine. Obtained results were analyzed using soft were SPSS version 16.0.
. There was a statistically increased difference between the mean of glucose, HbA1c, uric acid and creatinine among the test group when compared with control group (P=0.000) for all parameters respectively, as well as the mean ofGlucose, HbA1c, Creatinine and Uric acid between test group with <10years duration and test group with >10 years duration (p=0.000)
There was asignificant positive correlation between Blood glucose and plasma creatinine levels (r=0.399, p=0.000), also there was strong significant positive correlation between plasma levels of glucose and HbA1c % (r=0.760, p=0.000), and a significant negative correlation between plasma levels of Glucose and uric acid (r= - 0.323, p= 0.001) as well as with HbA1c (r= -0.305, p=0.002).
It was concluded that some parameter such as uric acid and creatinine were increased by type 2 diabetes mellitus and this increasing is directly proportional with the duration of DM, accordingly Diabetes mellitus type 2 could be causative disease for development of renal impairment.
