Evaluation of High Sensitive C Reactive Protein Level in Type II Diabetic Sudanese Patients in Khartoum State

Abstract

Background: Inflammatory markers such as CRP has been related to inflammatory disease, previous studies have been established to link between CRP and Cardiovascular disease specially in DM patients. This study aims to evaluate hs-CRP level as a predictor marker for cardiovascular diseases among uncontrolled type II diabetic patients in Khartoum state. Materials and Methods: One hundred and twenty individual were enrolled in this study, classified into 60 type II DM patients and 60 apparently health as control group. Serum hs-CRP and whole blood glycated hemoglobin were measured using immunoturbidymetric method and florescence sandwich immune-detection method, respectively. Results: The results showed hs- CRP level is higher in type II DM with P-value 0.000 specially uncontrolled DM patients with P-value= 0.006, also positive correlation between hs- CRP and duration, HbA1C with P-value = 0.002 , P-value =0.000 respectively. No correlation between hs-CRP when associated with BMI and age with P-value =0.59, P-value =0.15 respectively. Conclusion: The study concluded that, hs-CRP is higher in type II DM especially uncontrolled DM patients, in fact that, hs-CRP used as a marker for cardiovascular diseases.