Abstract:
This study was conducted to measure serum levels of plasma lipids (TG, TC, HDL-c
and LDL-c) in patients with chronic renal failure. Seventy fife random samples were
collected from patients were alredy attended ALnaw Teaching Hospital during the
period between January to march 2015 chosen randomly and seventy fife apparently
healthy individuals were selected as controls.
Enzymatic method was used to estimate serum lipid profile levels manually using
Biosystem kits and by using Mindary, and results were analyzed using (SPSS)
computer program (T- test and ANova test).
The results showed that serum levels of TG,TC, and LDL were significantly
increased (p-value = .000) (p-value = .001) (p-value = .000) respectively and the
serum levels of HDL were significantly decreased (p-value = .000) in the Sudanese
patients group.
TG serum level increasd between (101.5±35.8) in control to (132.2±56.3) in patients,
TC also increased to (138.0±42.0) compared to control (121.6±23.0). LDL showed
the same pattern and significantly increased to (133.8±43.1) in compare to control
(92.8±37.8). HDL of patients decreased to (31.8±4.0) while in control was
(37.0±5.4).
According to causes of renal failure the results of this study showed that;
hypertension, diabetes and family history are the most common causes in Sudan.
The results of this study showed that there is a weak correlation between TG levels
and duration of hemodialysis at (r = .223, p-value=.054). No correlation between TC
(r=.166, p-value =.154), HDL-c (r=.166, p-value =.156) and LDL-c (r=.133, p-value
=.254) levels and duration of dialysis was observed.
In conclution: the serum levels of TG,TC, and LDL significantly increased in
Sudanese all patients, but serum levels of HDL significantly decreased in all patients
subjected them to risk of many complications.
