Characterization of Myocardial Infarction and Therapeutic Response using Echocardiography

Abstract

The term "myocardial infarction" focuses on the myocardium (the heart muscle) and the changes that occur in it due to the sudden deprivation of circulating blood. The main change is necrosis (death) of myocardial tissue. The word "infarction" comes from the Latin "infarcire" meaning "to plug up or cram." It refers to the clogging of the artery. Myocardial infarction (MI) is a major health problem, with relatively high rates of morbidity and mortality. Among epidemiologists, there has been increasing interest in the characteristics of communities that influence health. The aim of this study was to measure the predisposing factors of MI versus some parameters and to test the response of MI to treatment. This study was conducted in the period of July 2012 to June 2014 in the ultrasound department of the Sudan Heart Center in Khartoum-Sudan, 250 participants (67.2% males and 32.8% females) and their ages range from 22 to 86 years; mean age of 41 ± 1.2 years were included in this study. Echocardiography studies were performed using MyLab 50 XVision-Esaote echocardiography machine equipped with 2.5 MHz phased array probe. Statistical Package for the Social Sciences (SPSS) was used to analyze the results. The mean and standard deviation (SD) of left ventricle ejection fraction before prescribed drugs was (43.10±4.2). This study had demonstrated a significant increase in left ventricle ejection fraction occurred after treatment with drugs (p <0.001). The value after used treatment ranged from 25 to 75 with mean and standard deviation 56.8±8.7 %. The study confirm that echocardiography is a valuable tool for evaluation of patients with myocardial infarction. This study conclud that; age, gender, body mass index, place of residence and patient history show significant association with myocardial infarction risk worldwide (p <0.001).