Association of Diabetes Mellitus type2with ABO and Rhesus Blood Groups in Sudanese Patients in Khartoum State

Abstract

This is a case control study .The objective of the study was to determine the association between ABO/Rhesus (Rh) blood group and diabetes mellitus type 2 in Sudanese patients. The study was conducted in Khartoum Teaching Hospital during the period January to July 2015Hundred diabetic subjects of both sexes and with different ages were enrolled randomly in this study and another hundred healthy non diabetic subjects of both sexes and different ages were taken randomly as a control group. Venous blood samples were taken from all the participants and ABO/ RH blood groups was determined by direct and indirect tube methods. The datawere analyzed by one sample Chi square test using SPSS version 16 . The results showed that there was no significant difference in the frequency of ABO blood group between type 2 diabetic subjects and the control group (P.value = 0.85).The frequency and order of the ABO blood group distribution in both the diabetics and the control group was O (42%vs 44%) , A (33% vs 33%) , B (21% vs 18% ) and AB (4% vs 5%).No significant variation (P.value = 0.37) was found in the frequency of Rh positivetype between the diabetic subjects (94%) and the control group (96%).The gender did not affect the order of distribution ABO blood group or the Rh type in the diabetic subjects. It is concluded that there is no association between ABO/Rh blood group and DM type two or the gender.