Abstract:
This study was carried out to measure serum levels of the liver enzymes;
aspartate transaminase and alanine transaminase in patients with renal
failure under hemodialysis. Eighty samples were collected from patients
in period between January to March 2015, chosen randomly
from
ALnaw teaching hospital and Alrebat teaching hospitals, and forty
apparently, healthy individuals as controls, to assess the effect of
hemodialysis on liver transaminases enzymes level.
Measure serum aspartate transaminase and alanine transaminase were
measured by using autoanalyzer mindray BS 200, and results were
analyzed using statistical of package social science (SPSS), computer
program.
The study showed that the serum levels of aspartate transaminase" AST",
and alanine transaminase "ALT" were significantly decreased, (p-value
=0.00) in the patients under hemodialysis group. Mean±SD controls
versus cases. (34±7versus15±5u/l) for AST, (24±7 versus 10±4 u/l) for
ALT.
Also the serum levels of liver transaminase enzymes were measured in 20
cases with renal failure under hemodialysis, to compare the levels of them
before dialysis and post dialysis, showed (AST&ALT) were significantly
decreased (p-value=0.00) in cases before dialysis when compared to the
levels of them after dialysis. Mean ± SD for predialysis versus post
dialysis. (13±4 versus 22±4u/l) for AST, (8± 4 versus 17± 3 u/l) for ALT.
The study indicates that there was no significant difference between the
levels of liver transaminase enzymes according to gender "males or
females". The results as follow;
