Abstract:
The main aim of this study was to determine the seroprevalence of
Epstein Barr Virus (EBV) (VCA) IgG antibodies using enzyme linked
immunosorbent assay (ELISA), among blood donors attending Blood
Bank Department at National Public Health Laboratory in Khartoum
State, from January to February 2015 .
A total of 90 subjects were included , 75 blood donors and 15 controls
with age ranging from 18-63 years . The results revealed that the
prevalence of EBV (VCA) IgG in the total samples were 83(92.2% ) and
among blood donors was 69(92%) ، while 14(93.3% ) in control subjects .
Possible risk factors were examined in this study including age , sex,
marital status , major blood groups and previous blood transfusion. All
these showed no significant effect ( P> 0.05 ) on EBV IgG antibodies
among both blood donors and control group.
The results obtained showed that the prevalence of Epestin Barr Virus
(VCA) IgG antibodies among both blood donors and control group
increased with age,while it was 58(90.6%), 13(92.8%) in male,
11(100%), 1(100%) in female, 43(93.4%), 6(85%) in single, 26(89%),
8(100%) in married and 2(100%), 0(0%) in previously blood transfusion
respectively.
The results showed that EBV is endemic in Sudan . Although primary
EBV infection among normal immunocompetant individuals is not one of
the clinically serious viral infections in Sudan, but the serious
complications of diseases that occur in immunocompromised individuals
(transplant recipients and AIDS) can not be neglected . This study
recommends the screening of blood for EBV antibodies among blood and organ transplant donors
