Evaluation of target Volume localization and Dose Estimation for Pituitary Adenomas 2D and 3D Radiation Dose Distribution

Abstract

The general objective of this study was to evaluate pituitary adenoma treatment with radiotherapy modalities that will lead to escalate radiation to the surrounding normal tissues causing complications. The sample of the study consists of 300 patients; with age ranging from 17 to 57 years old. The CT simulator was used to collect data in order to delineate pituitary adenoma including growth target volume (GTV) and planning target volume (PTV 95%) as an isodose surface for treatment in order to obtain dose distribution in 3D dose coverage to the target while sparing organs at risks. The result of this study showed that, the pituitary adenoma treatment was a subject of researches likely many scholars findings show the complications occurred during the treatment with radiotherapy without mentioning the suitable technique to reduce radiation the surrounding tissues in accordance to this study findings shows the 3D dose distribution technique reduces the unnecessary dose to the surrounding tissues (temporal lobe, optic chiasm, eye) ; 3D dose distribution is safe to the target volume, while the average dose reaching the organs at risks were as follow: temporal lobe 1.14 Gy, eye 0.86 Gy, and optic chiasm 0.95 Gy more than a 2D dose distribution during the treatment