ASSESSMENT OF RENAL FUNCTION IN SUDANESE HYPERTENSIVE PATIENTS

Abstract

The kidney function was monitored in 70 hypertensive Sudanese patients from Khartoum state in order to assess the impact of hypertension in function of kidney in those patients. Other 30 none hypertensive individuals were also participated in this study to serve as control. Patients and controls were matched in age and sex in which the average age of patients was 52 years. Five ml of blood are taken left to clot, then centrifuged to obtain serum which used for estimation of Electrolytes Na+ & K+ by flamephotometer, while Creatinine by Jaffe reaction and Albumin by bromocresol green method by means of colorimeter and clear urine analyzed for protein excretion by sulphosalycylic acid method. The findings obtained from this study revealed that the majority of the hypertensive patients are elderly, over 52 years and most of them presented with many clinical complications of cardiovascular diseases and coronary events. The study also showed that family history of hypertension was present among close relative of the study group. Measuring electrolytes Na+ & K+ in the serum of the hypertensive patients of this study showed highly significant increase level of Na+ compared to control (P<0.05), while K+ level showed no statistical difference between patients and controls values (P>0.05). On the other hand Creatinine and Albumin showed highly significant elevation in patients over ‫‪that‬‬ ‫‪suggest‬‬ ‫‪may‬‬ ‫‪result‬‬ ‫‪This‬‬ ‫.)50.0>‪(P‬‬ ‫‪values‬‬ ‫‪control‬‬ ‫‪hypertensive patients participated in this study at high risk to‬‬ ‫.‪develop kidney disease and its complications‬‬ ‫‪A result which may suggests that hypertension is an individual‬‬ ‫.‪risk factor leading to kidney disease‬‬