Frequency of H. pylori Antibodies among Patients with Gastrointestinal Symptoms Attending Khartoum Teaching Hospital

Abstract

A total of 90 patients with gastrointestinal symptoms, and who attending Khartoum Teaching Hospital during the period from April to October 2012, were enrolled in this study. Out of them 35 (38.9%) were males and 55 (61.1%) were females, their age ranges from 15-60 years with mean (33.2).The aim of this study was to detect frequency of Helicobacter pylori IgM, IgG antibodies, and to determine the relationship between the presence of antibodies and certain factors such as (sex, age and genetic susceptibility). 90 serum specimens were collected from patients, and analysed by ELISA technique. The results showed that 19 (21.1%), 57 (63.3%) were positive for IgM antibody and IgG respectively, while 15 (16.7%) were positive for both. Females were more affected than males, high frequency of positive results was observed among 15-30 age groups. Statistical analysis showed that there was insignificant correlation between age, gender, genetic susceptibility and presence of Helicobacter pylori ‫antibodies (P >0.05).