Sero Detection of Herpes Simplex Virus type 1 (HSV-1) IgG Antibody among Pregnant Women in Ombada and Fedail Hospital, Khartoum State

Abstract

Herpes simplex virus -1 is a viral infection that causes genital and oral herpes. Which can affect in pregnant and new born cause spontaneous miscarriage or skin rash. This cross section study was aimed to detect anti-herpes simplex virus type 1 (HSV-1) IgG antibodies among pregnant women during the period from April to June 2022 in Ombada and Fedail Hospital, Khartoum State. Out of 96 investigated specimens; there were 65(67.7%) were anti-HSV-1 IgG positive and 31(32.3%) were negative. In which 29(44.6%) had history of miscarriage and positive for anti-HSV-1 IgG and 35 (53.8%) had no previous miscarriage and positive for anti-HSV-1 IgG antibodies. Concerning gestational age; there were 33(50.7%) in second trimester, 17(26.1%) in first trimester and 15(23%) in third trimester were positive for anti-HSV-1 IgG antibodies. Regarding age groups; there were 31(47.6%) in age group 25-33, 21(32.3%) in (34-42) and 13(20%) in 16-24 were positive for anti-HSV-1 IgG antibodies. This study concluded that; there is no significant statistical difference between history of abortion in pregnant women and HSV-1 infection and also no significant association between HSV-1 infection and Gestational stage.