GC-MS Analysis And Antimicrobial Potency of Five Sudanese Medicinal Plants

Abstract

In this study, the oil from five potential medidinal plants have been extracted by maceration with n-hexane. The constituents of the oil have been characterized by the hyphenated technique: GC-MS.Furthermore, the antimicrobial activity of the oils has been evaluated using the agar diffusion bioassay. GC-MS analysis of Cassia sieberiana, Kigelia africana seed oil both of them dominated by 9,12-octadecadienoic acid(Z,Z)-, methyl ester and 9-octadcenoic acid (Z)-, methyl ester respectively, but 9,12,15-octadecatrienoic acid methyl ester only dominated in kigelia Africana. Also 9,12-octadecadienoic acid(Z,Z)-, methyl ester and 9-octadcenoic acid (Z)-, methyl ester appeared as a major component in Acacia seyal, Ziziphus spina Christi, and Vitex doniana in different percentage.The target oils were evaluated for their antimicrobial potential using the agar diffusion bioassay. The oils gave different antimicrobial responses.