Plasma Aminotransferases Activity Levels among COVID -19

Abstract

Background: Corona virus disease is challenging in everyday lives because it has devastating effects on human health and well-being and negative impact on economy. Aim: This study was amid to assessment plasma aminotransferases activity levels among COVID -19 patients at Khartoum state. Methods: This was case control study conducted during the period from faraway to June 2022. fiftieth patients with COVID -19 collected as case group compared with fiftieth healthy volunteer as control group. Blood samples were collected from both groups and plasma activities of aminotransferases were estimated using full automated spin 200 instrument. the procedure of biochemical test was performed according to manufactured instruction, statistical analysis was done using SPSS version 25 Results: The mean of plasma AST, ALT were significantly higher in COVID - 19 patients (62.08u/l,47.6 u/l) when compared with control group (28.2,21.3) with p value (0.00) also this study shows no significant different in mean of AST, ALT levels between gender (male, female )in case group (51.3)(39.1) ,(66.2,52.7) with p value (0.23,0.195). This result showed no correlation between AST levels and age with p value (0.113) R (0.159) on the other hand their correlation between ALT levels and age p value (0.003) R (0.294). Also showed no correlation between AST, ALT levels and duration of disease with p value (0.215, 0.182) R (-0.178, 0. 192). Conclusion: COVID -19 patients had high levels of AST and ALT, with ALT levels increased due to aging.