Chemical Constituents and Antimicrobial Activity of Oils Extracted From Five Sudanese Medicinal plants

Abstract

In this study the oils from five plants ofmedicinal atteributtes (Sesabania sesaban , Dichrostachys cinarea , Cordia sinensis , Acacia polyacantha ,and Peganum harmala ) have been studied by GC-MS and antimicrobial activity has been screened . Gas chromatography – mass spectrometry has been used for the identification and quantification Sesabania sesban oil. The analysis revealed the presence of 20 components dominated by cis-9-Hexadecenal (14.75%).The oil however failed to show any activity in the cup plate agar diffusion bioassay . Gas chromatography – mass spectrometry analysis of Dichrostachys cinarea oil showed the presence of 11 components dominated by 9-Octadecenoic acid (Z)-, methyl ester (41.66%) . The oil did not exhibit any antimicrobial activity. The GC-MS was conducted for Cordia sinensis oil . The analysis revealed the presence of 32 components . Major constituent being 9-Octadecenoic acid (Z)-, methyl ester (27.09%) . The studied oil failed to show any activity against all test organisms. The GC-MS was conducted for Acacia polyacantha oil. The analysis revealed the presence of 37 components dominated by 9,12-Octadecadienoic acid (Z,Z), mthyl ester (31.24 %). The studied oil exhibited significant activity against Echarichia coly(G-ve) and Psendomonasaeroginasa (G-ve) Candida albicans (fungus). Analysis of Peganum harmala oil revealed the presence of 23 components components dominated by 9,12-Octadecadienoic acid (Z,Z), mthyl ester (54.14 %). The studied oil exhibited significant activity against Echarichia coly(G-ve) and Psendomonasaeroginasa (G-ve) Candida albicans (fungus). Staphylococcus aureus(G+ve). The oil exhibit significant antioxidant activity compared to the positive control.