Estimation of reference value of Thyroid Uptake and its Correlation to Thyroid Function Test in Sudanese

Abstract

The aim of this study is to describe the thyroid uptake in Sudanese population by scintigraphy and to correlate this uptake with their clinical results of Thyroid Function Test (TFT). Thyroid uptake and their TFT clinical results were recorded in a sample of 99 patients and presented with clinically suspected thyroid gland diseases given the presence of anxiety, irritability, nervousness, trouble sleeping, losing weight and an enlarged thyroid gland symptom. The average thyroid uptake was (11.07 ± 2.8) for the total dataset; it was higher in hyperthyroidism (19.68 ± 5.27) than in normal (1.924 ± 0.61). In the statistical analysis, thyroid uptake was correlated with all TFT measures, it was found that T3, T4 have a positive correlation with the uptake while TSH has a negative correlation with it. A predictive model for uptake values inspection was created using multiple linear regression. Therefore, a specific reference values of thyroid uptake as a function of clinical TFT results in Sudanese population, could be used for evaluating thyroid uptake in clinical practice.