Effect of Ramadan Fasting on Platelet Indices and C - reactive protein in Patients with Rheumatoid Arthritis in Khartoum state

Abstract

This is a cross-sectional case-control study conducted in rheumatic patients and healthy volunteers as control group at Omdurman Military Hospital and Rayan Specialized Laboratory in Khartoum state from May to November 2019. The study included 60 Sudanese rheumatic patients, 30 of them were fasting and other 30 were non fasting and 60 healthy individual as control. All participant age was between (26-69) years.Data was collected by using laboratory investigations and questionnaire. 5ml of venous blood sample was collected from each participates in containers containing EDTA and plan containers, analyzed automatically to measure platelets count and platelets indices and C-reactive protein .The data analyzed using SPSS(version 20.0)computerized program. The result showed that there is no significant difference between the fasting andnon-fastingpatients in the platelet count (P ≥ 0.320) andMPV (P ≤ 0.324) andPDW (P ≤ 1.000) and PCT (0.115).Higher significant different between the fasting andnon-fasting in the hs-CRP (P ≥ 0.000).The result showed that there is high significant different between the case (RA patients) and control (normal healthy individual) in the platelet count and MPV and PDW and PCT (P=0.000). Dietary changes during Ramadan could be effective to a reduction the inflammatory response in patients with RA.