Estimation of Normal Homogenous Thyroid uptake using Technetium- 99mRadiotracer

Abstract

The main objective of this study was to evaluate the normal range of thyroid uptake and determine the thyroid volume in patients who has normal thyroid function test (T.F.T) (mean of normal range of these patients T3: 3.1-6.8 p, mole/L, T4: 10-24.5 p mole/L & TSH: 0.2-5.5 miU/L) & homogenous distribution of the radiotracer in Sudanese especially in Radiation & Isotope Center Khartoum (RICK) & Elnelain Medical Diagnostic Center. This study includes 400 patients (85.5% female, 14.5% male) in different age, sex, center of origin and type of food and drink intake, for nine months From May 2017 to May 2020. The most frequency of ages distribute as (18-27 36.3%, 28-37 28.5% ) the thyroid uptake value in the gamma camera (mediso) & (simens), the result of this study showed that, the normal range of thyroid uptake is in the range between (0.4% —5.0%) & the thyroid volume is in the range of (11.6cm2 to 36.7cm2) there was a direct relationship between thyroid uptake and the thyroid volume that when the volume increase the uptake increase that shown in the following equation: y = 2.98+7.08E-3*x where x refers to thyroid volume and y refers to uptake in percent. The result also shown that when weight increase the uptake decrease as shown in the following equation: y = 2.18+x + 0.01*x where x refers to patient weight in Kg and y refers to up take in percent. The result shown that high uptake young patient in age between 18 -37 years and slightly stable (reasonable high and low) under fifty, then increase to be high again. The increasing of high uptake in age 18-37 years known area of changes in hormonal activity to be stable, then it becomes slightly stable till below 50 and after that go to increase.