Assessment of Prolactin level, Cholesterol and Triglyceride among Women with Polycystic Ovary Syndrome

Abstract

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrinopathy characterized by both reproductive and metabolic abnormalities.This study was carried out to evaluate serum prolactin, cholesterol and triglyceride in poly cystic ovary syndrome woman in Khartoum state. Methodology: The study was carried on one hundred volunteer in reproductive age include 50woman as case and 50 as control at DR AL SIR Abo- Alhassan infertility center from may to November (2019),venous blood samples was collected ,processed ,and analyzed .prolactin level was estimated by Enzyme linked immune sorbent assay technique and cholesterol and triglyceride level were estimated spectrophotometer biosystem -310.Experimental case-control methodology was done. The obtained resultwere analyzed statistically by using of SPSS software program. Result: The level of prolactin wasincrease significant with (p-value=0.000),also cholesterol significant increase (p-value= 0.009)and triglyceride (p-value=0.001). In poly cystic ovary syndrome patient compared to control group according to infertility ,duration of disease menstrual regulation ,family history ,cosmetic and use medication ,the study showed that prolactin increase insignificant with infertility ,therapy ,cosmetic and history with (p.value=0.124) ( p.value=0.761 )( p.value =0.611)( p.value= 0.986) respectively. But cholesterol increase significant compared with infertility with (p.value=0.031) and insignificant with therapy (p.value=0.908), cosmetic (p.value=0.786) and menstrual cycle (p.value=0.180). Triglyceride increased insignificantly with infertility (p.value=0.430), therapy (p.value=0.084) cosmetic (p.value=0.137) and menstrual cycle (p.value =0.721).