Serum Phospholipids Levels in Sudanese Patients with Type 2 Diabetes Mellitus

Abstract

The prevalence of type 2 DM has been increasing significantly in all countries during the last century. It is widely recognized that the most serious problem in DM arises from the insidiously developing vascular complications. This is a cross-sectional study, aimed to determine the level of serum phospholipids in Sudanese patients suffering from diabetes mellitus type 2, during the period of April 2010-july 2010. Fifty samples were collected from Almotkamil centre. The study included both sexes, 25 males aged (45-70years), whereas, 25 were females aged (45-68years). 2.5 mls of venous blood were taken from each patient in lithium heparin container, serum was obtained in plain container, and the samples were analyzed for serum phospholipids levels using spectrophotometer. Statistical analysis of the results showed that, the means of serum phospholipids in diabetic patients was higher( 275.82 mg/dl, p. value 0.000) compared to the reference value of phospholipids levels. From the result of the present study, it is concluded that; the plasma phospholipids levels represent a marker for accelerated atherosclerosis, particularly in type 2 diabetic patients. Thus, measurement of plasma phospholipids could be useful for the stratification of cardiovascular risk.