Evaluation of Platelet Count and Platelets Indices in Type 2 Diabetes Mellitus in Sudanese Patients –Qadarif State

Abstract

Background: Diabetes mellitus (DM) has been considered as a prothrombotic state with enhanced platelet reactivity. Platelets indices have been altered in patients with DM type 2. Objectives: The aim of this study to evaluate the platelets indices among Sudanese patients with type 2 diabetes mellitus. Materials and methods: This is a case control study carried out in AL-Faw Teaching hospital - Al Qadarif State during May 2018 to July 2018, to evaluate the alteration in platelets count, mean platelet volume (MPV/ fl), platelet distribution width (PDW/fl) plateletcrit (PCT/%) and platelet large cells ratio (P-LCR%), in Type 2 Diabetes Mellitus Sudanese patients. Sixty diabetics and sixty healthy individuals were enrolled in the study after taking their verbal consent. Result: The results were showed a significant increase in mean platelets volume(MPV) among diabetic patients when compare with non-diabetics (9.45 ±1.42 vs 7.976 ± 1.249 / fl), PDW / fl (13.97±1.63 vs. 11.74±1.62/ fl), P-LCR% (14.98± 0.91 vs. 12.240± 1.82 %) and significant decrease for platelets count (258.50± 32.164 vs.284.12 ± 1.249) x 109 /L, PCT% did not vary with T2DM. The duration of DM type 2 did not (P ≤ 0.05) alter any of the studied parameters. PLT count c/cmm, MPV fl, PDW fl, PCT % and PLCR% did not vary with the level of glycemic control. Conclusion: the study was observed that Type 2 diabetes mellitus altered some of the platelets indices and count.