Frequency of Pulmonary Candidiasis Among Hospitalized Patients with Respiratory Tract Diseases Attending El-Shaab Teaching Hospital -Khartoum State

Abstract

This was cross sectional study aimed to determine the frequency and etiology of Pulmonary Candidiasis, conducted during the period from February to June 2018 at Elshaab Teaching Hospital (Khartoum State). Hundred hospitalized patients with respiratory tract disease suspected to have Pulmonary Candidiasis were enrolled in this study, both gender males and females were included in this study. Sputum specimens were collected from all suspected patients, and subjected to Gram’s stain, 10% potassium hydroxide (KOH) wet mount, culture and biochemical tests for identification of pathogens. Among total 49/100 (49%) were males and 51/100 (51%) were females, their age varies from 20 years to 80 years with a mean of 44.1 ± 13.5 years The frequency of Pulmonary Candidiasis was 9/100 (9%), and all isolates 9/9 (100%) were Candida albicans. High frequency rate of Pulmonary Candidiasis was observed among patients with cancer 3/9 (34%). The frequency of Pulmonary Candidiasis in patients with in ages between 60-80 years 6/9 (67%) There was generally a higher frequency of Pulmonary Candidiasis especially in elderly paitents compared to other age group. Statistical analysis showed that there was significant association between Pulmonary Candidiasis and both clinical history and age of patients, while there was no significant association between Pulmonary Candidiasis and gender of patients. P value (0.00, 0.001, 0.774) respectively.