Association of Gamma Glutamyl Transferase,Cholesterol and Triglycerides among Type 2 Diabetic Patients in Khartoum State

Abstract

Association of gamma glutamyl transferase, cholesterol and triglycerides among type 2 diabetic patients this cross sectional , case-control study, conducted in Abdullah Khalil Center for diabetes , during the period of March to May 2018 . Analytical and statistical methods were applied to investagate association of serum GGT, cholesterol and triglycerides in diabetic patients. A total of 95 patients were enrolled in this study 50 of them were diabetic patients with mean age 53 years. 20 of them were male and 30 were female. The other 45 were apparently healthy individuals represent control group with mean age 46.05 years. Blood samples were collected and analyzed for serum GGT, cholesterol and triglycerides , the results then were statistically analyzed by SPSS . The results showed that , there was a significant increase of GGT levels in patients (24.28 + 11.1) when compared to the control group (19.56 + 9.4) with a P.value (0.029) In addition , there was significant increase of triglycerides levels in patients (184.78 + 114.5) when compared to the control group (130.62 + 68.3) with a P.value (0.006), and no significant different of cholesterol levels in patients (192.86 + 45.3) when compared to the control group (186.22 + 50.7) with P.value (0.502) . There was positive correlation between GGT and triglycerides with( P. value =0.013, r=0.348) and no correlation between GGT and cholesterol with (P.value =0.125, r=0.220) , BMI (P.value=0.332, r=0.140) , FBS ( P.value =0.187, r=0.190) . In conclusion : diabetics had Higher GGT and Triglycerides level with normal cholesterol. GGT correlate positively with triglycerides .