Frequency and Susceptibility Patterns of Streptococcus pyogenes among Children Patients with Tonsillitis in Khartoum Teaching Hospital

Abstract

The aim of this study was to determine the frequency of Streptococcus pyogenes in throat swabs and serum specimens among children patients with tonsillitis. A total of 100 throat swab specimens collected from Khartoum State in Khartoum Teaching hospital during April to June 2012. Bacteriological analysis of throat swabs were performed for Streptococcus pyogenes including inoculation on sheep blood agar and on crystal violet blood agar. Susceptibility testing was carried out for each isolate.100 specimens were collected from suspected tonsillitis each specimen involved blood for serological purpose and swab for culture purpose Out of the 100 throat swab specimens; 32 (32%) Streptococcus pyogenes was recovered from patients with age ranging from 5 to15years. The 32 isolates were susceptible to Bacitracin, Amoclane, azithromycin, penicillin, ciprofloxacin, gentamycin, ampicilline and erythromycin but they were resistant to cotrimoxazole. This study showed that Streptococcus pyogenes considered to be one of the important respiratory tract pathogens in children particularly with an age ranging from 5 to15years old. Since antibiotic therapy should be guided by in-vitro susceptibility tests. All serum samples examined ASO test using slide and tube method, the result showed 2o% and 18% seropositive for slide and tube method respectively.