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Please use this identifier to cite or link to this item: https://repository.sustech.edu/handle/123456789/16863
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dc.contributor.authorAhmed , A.M.
dc.contributor.authorMohamed , O. S. A.
dc.contributor.authorHomeida , Mohamed .A.M.
dc.date.accessioned2017-04-30T06:53:01Z
dc.date.available2017-04-30T06:53:01Z
dc.date.issued2012
dc.identifier.citationAhmed , A.M. . Effects of Guru (Cola nitida) on Drug Metabolizing Enzymes in Rats / A.M. Ahmed , O. S. A. Mohamed , Mohamed .A.M. Homeida .- Journal of Science and Technology .- vol 13 , no 2 .- 2012 .- article .en_US
dc.identifier.issnISSN 1605-427X
dc.identifier.urihttp://repository.sustech.edu/handle/123456789/16863
dc.descriptionarticleen_US
dc.description.abstractThe objective of this study was to investigate the effect of guru on drug metabolizing enzymes in rats. Guru at a dose of 100mg/kg administered orally to rats caused induction of hepatic microsmal mixed function oxidase , but at the dose of 200 and 400 mg/kg inhibited the drug metabolizing enzymes compared to controls that were given rat diet . It is concluded that guru may produce pharmacological effects at the dose of 100mg/kg and toxicological effects at higher doses.en_US
dc.description.sponsorshipSudan University of Science and Technologyen_US
dc.language.isoen_USen_US
dc.publisherSudan University of Science and Technologyen_US
dc.subjectAminopyrine-N-demethylase , Aniline-4-hydroxylase, UDP-glucuronyltransferase Glutathione-S-tranferase, Cytochrome p-450en_US
dc.titleEffects of Guru (Cola nitida) on Drug Metabolizing Enzymes in Ratsen_US
dc.typeArticleen_US
Appears in Collections:Volume 13 No. 2

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