Antimicrobial Susceptibility of (Rumexvesicarua) Extractand Commonly Used Antibiotics against Aerobic Bacteria Isolated from Wound Infection of Diabetic Patients in Khartoum State

Abstract

This is a across sectional study, aimed to identify the aerobic bacterial pathogens associated with diabetic wounds in Khartoum State and testing the antimicrobial susceptibility of the most commonly used antibiotics in treatment of wound diabetic person comparison with the activity of plant extract, in the period between February to August, 2016.Fifty wound swab samples were collected and cultured in MacConkey and Blood agar medium. After identification, the isolates were subjected to antimicrobial sensitivity usingAmikacin, Cotrimoxazol, Imipenam, Ciprofloxacin for Gram negative bacteria,and Erythromycin,Tetracycline,Penicillin andGentamicinfor Gram positive bacteria.Then, the isolated organisms were also subjected to plant fruits extract (Rumexvesicarus) to test their antimicrobial activity. The results revealed that Staphylocoocusaureus and Pseudomonasaeruginosa were the predominant pathogens in diabetic wound infections. The Amikacin and Imipenamshowed 100% activity against isolated bacteria when compared with other standard antibiotics, theaqueous extracts of Rumexvesicarus gave a high percentage of activityagainstProteus mirabilis(28%) andthere was no any activityagainst Escherichia coli. Further studies in Rumexvesicarusin other parts of plant must be done,to detect if they have any antimicrobial activity.