Determination of Complete Blood Cell Count of Sudanese Pregnant Women at First Trimester attended hospitals in Bahrilocality

Abstract

This was a case control study, conductedatBahrilocality during the periodfrom July toNovember 2015. Aimed to determine Hb, RBCs, PCV, MCV, MCH, MCHC, Platelets,TWBCs, Leukocyte differential count of Sudanese pregnant women at first trimester of pregnancy attended Almokhtabar laboratory. Eighty healthy pregnant women and eighty non pregnant women were informed about the study and agreed for participation. A questionnaire was designed to collect information about the study group such as age, number of pregnancies, stage of trimesters, history of abortion and whether they visit the clinics regularly. Three ml of venous blood was collected in EDTA anticoagulant container. Automated hematological analyzer (Sysmex XS800i) was used to measure complete blood cell count. The study revealed that mean of Hb (11.6 g/dl ±1.3), RBCs (4.1×109 / L ±0.5), PCV (33.8%±3.3), platelets (250×109 / L ±64.9), and lymphocytes (28.0% ±8.0) of pregnant women decreased significantly (p.values 0.03, 0.004, 0.00) respectively compared to non pregnant women whom their mean of Hb (12.6 g/dl ± 1.7), RBCs (4.2 ×109 / L ±0.5), PCV(36.7 % ±4.1), platelets (315×109 / L ± 92.9) and lymphocytes (35.7% ± 10.9). TWBCs (6.6×109/L ±2.0) and neutrophils (62.9%±9.5) were increased significantly (p.values 0.05, 0.01) respectively compared to non pregnant women TWBCs (6.0 ×109 / L ±1.8) neutrophils (55.8% ±11.4) but MCV (82.4fl±5.2), MCH (28.3pg ±2.5), MCHC (34.3% ±1.7) and mixed count (9.3%±3.7) increased insignificantly (p.value= 0.40, 0.90, 0.40, 0.30)respectively.

According to age groups in pregnant women therewas no statisticalsignificant in CBC and number of pregnancies as well ashistory of abortion.