Determination of Rhesus Antigens Frequency among Blood Group A and O of Pregnant Sudanese Women in Khartoum State

Abstract

This is a descriptive cross-section al study carried out at Reproductive Health Care Centre in Khartoum state. during the period from August 2015 to November 2015, to determine the frequency of Rh antigens among Sudanese pregnant ladies group A and group O, compare the frequencies of rhesus antigens between group A and group O Sudanese pregnant ladies and to detect if there are significant role for c antigen in the previous abortion.by using direct tubes technique , One hundred blood samples were collected from participate enrolled in this study, 50 samples from Sudanese Pregnant Ladies group A, 50 samples from Sudanese Pregnant Ladies group O. 10 samples from Sudanese Pregnant Ladies group A with no previous abortion history ,10 samples from Sudanese pregnant Ladies group O with no previous abortion history Also were include in this study as control. 2.5 ml of venous blood were drown from each pregnant ladies in K2EDTA container. Rhesus phenotype was determined by using direct group method. The result show that the frequency of Rh Antigens among pregnant Ladies group (A) with (+ve) Rh as(52) anti-D ,(41) anti-c ,(38) anti-e ,(23) anti-C ,(10) anti-E.and the pregnant Ladies from the same group with (-ve) Rh as (50) anti-E ,(37) anti-C , (22) anti –e , (19) anti –c ,(8) anti-D. And pregnant Ladies group (O) with (+ve) Rh as (54) anti-D ,(40) anti-c ,(39) anti-e, (24) anti-C ,(13) anti-E.and the pregnant Ladies from the same group with (-ve) Rh as (47) anti-E ,(36) anti-C ,(21) anti-e ,(20) anti-c ,(6) anti-D. The antigen-c can be consider as protective factor of abortion ,pregnant with –ve antigen-c are more susceptible to abortion when compare pregnant with +ve antigen-c.