Determination of Complete Blood Cell Count of Sudanese Pregnant Women at Second Trimester –Khartoum North Hospitals

Abstract

This is a case control study, conducted in Khartoum North during the period from February to July 2015, to determine CBC (Hb, RBCs, HCT, MCV, MCH, MCHC, Platelets, WBCs, Leukocyte differential count, RDW, and MPV) of 80 Sudanese pregnant women at Second trimester as case and 40 non pregnant women as matched age as control. Pregnant women at second trimester were informed about the study and agreed for participation as case. A questionnaire was designed to collect information about the study group such as age, number of pregnancies, month of pregnancy, history of abortion .Two and half ml venous blood was collected in EDTA anticoagulant container. Automated hematological analyzer (Sysmex KX – 21N) was used to measure Complete Blood Count, and the results were analyzed by independent T test of the SPSS computerprogramme. The results showedsignificant decreasein mean of Hct, TRBCs, Hb, MCHC and lymphocytes percentage( p≤ 0.05) in pregnant women when compared withnon pregnant women.TWBCs, PDW, MPV and neutrophils percentage significantly increase( P = 0.00). Insignificant decrease in means of MCV, MXD% and platelets in pregnantwomen(P.value≥ 0.08)when compared withnon pregnant women. Insignificant increase in means of MCH and RDWsd(P.value≥ 0.5). . No significant difference in means of Hb, Hct, TRBCs count and indices and TWBCs count and differential ,platelets and their indices (p > 0.13), between with and without abortion . There was no significant difference between means of Complete blood cell count in pregnant women(p>0.1) who’s had less or more than three children . There was no significant difference between means of Complete blood cell count in pregnant womenwho,s age more or less than 30 years. In conclusion , Hct, TRBCs, Hb, MCHC and lymphocytes and neutrophil percentage,TWBCs, PDW, MPV significantly affected by pregnancy at second trimester.