Determination of Complete Blood Cell Count of Sudanese Pregnant Women at the Third Trimester attended Khartoum Teaching Hospitals

Abstract

This is a case control study conducted at Khartoum state during the period from April to October 2015. The aim of this study is to determine the complete blood cell count of Sudanese pregnant women at third trimester of pregnancy. Eighty healthy pregnant women and 40 non pregnant women were informed about the study and agreed for participation. A questionnaire was designed to collect information about the study group such as age, number of pregnancies and history of abortion in pregnant women. Three ml of venous blood were taken in K2 EDTA anticoagulant container. Automated hematological analyzer (Mindary BC-3000 plus) was used to measure Complete Blood Count. The results showed that RBCs, Hb, MCHC, lymphocyte count, lymphocyte% decreased significantly in pregnant women (4.0×106/μl ± 0.46), (10.9g/dl ±1.24), (32.4g/dl±1.72), (1.9×103/μl± 0.59), (26.7% ±8.02) and (223×103/μl±61.0) compared to non pregnant women (4.3×106/μl ± 0.38 ), ( 12.2g/dl ±1.07), (36.1/dl± 2.07), (2.3×103/μl± 0.66), (37.9% ± 13.85) and (292×103/μl± 74.88) respectively (P.value = 0.00). While MCV, neutrophil count and neutrophil% increased significantly in pregnant women (84.6fl ±5.91), (4.9×103/μl±1.49) and (66.0% ±8.05) compared to non pregnant women (78.5fl ± 6.81), (4.1×103/μl± 2.59) and (55.0% ±16.74) (P.value ≤ 0.04). No significant differences in HCT, MCH, WBCs, and MXD of pregnant women when compare to non pregnant women (P.value ≥ 0.08). No significant effect of abortion, number of children and age on CBC of pregnant women. In conclusion, pregnancy affect RBC, Hb, MCV, MCHC, neutrophil, and lymphocyte significantly.