Characterization of the Thyroid diseases using Ultrasound Modes& Elastography

Abstract

This is a prospective, consecutive study of thyroid patients referred for ultrasound for the period of 2011 to 2014 at King Abdulaziz University hospital (KAUH) In Jeddah. Problem of the study lies in the interest research that have been made about the role of ultrasound imagine in monitoring differentiate benign from malignant thyroid nodule and lack of diagnosis to see who should the biopsies sample and who need to follow medical only. Importance of the study is to take advantage of the use of ultrasound system plasticity in description Thyroid disease monitoring predicting characteristics that indicate the presence of slag between thyroids nodules among patients in the study sample and comparing the results with results of cytology. Objectives of study are: ♦To take advantage of the characteristics of the ultrasound description of Thyroid disease ♦To evaluate the elastographic appearances of thyroid nodules. ♦To determine whether ultrasound elastography (USE) may assist in differentiating benign from malignant thyroid nodules. ♦To evaluate the diagnostic utility of conventional US and real time ultrasound elastography in differentiating degenerating cystic thyroid nodule with malignancy. The study monitored a sample of 300 patients (270 females, and 30 males). 300 nodules in 300 patient examined by B-mode Ultrasound and color flow Doppler showed 94 (31%) malignant nodules and 206 (69%) were benign with sensitivity of 72.4%, specificity of 78.7%, a positive predictive value of 93%, a negative predictive value of 41% .