Abstract:
This study was carried out in the Sudan ( Radiation &
Isotopes center- Khartoum) to assess the value of FNAC in
diagnosis of palpable thyroid masses and to improve quality of
FNAC. A comparison was made between the main three
cytological stains ( Haematoxylin and Eosin (H&E) stain,
Papanicolaou (Pap) stain and May-Grunwald Giemsa (MGG)
stain ). The study was carried on 108 patients during the period
from (December 2004 to December 2005).
The study found that FNAC had sensitivity of 83.3% and
specificity of 100%, in differentiation between malignant and
benign thyroid palpable masses. The benign thyroid tumor
conditions were 96.3 % (104 cases). While Malignant thyroid
tumors were 3.7% (4cases).
The mean age for our study population was 38.2 years.
The females were more than males and they account for 87% of
cases. 27.8% of cases were from Bagara tribe Also the major
residence was the west of Sudan (35.2%).
The Pap stain and H&E stain showed best stain quality
concerning background and deposit .Both had total mean of
90.97% on the other hand MGG had total mean (79.3%).
The Pap stain showed best stain quality concerning nuclear
staining with mean of (94.03%). H&E stain came next with
mean of (90.83%) and MGG came last with mean of (86.11%).
The Pap stain showed best stain quality concerning
cytoplasmic staining with mean of (93.61%) and H&E stain
came next with mean of (88.75%). MGG came last one with
mean of (83.61%).
The pap stain showed the best total quality for the staining
of FNAC .H&E came next and MGG came last according to
our results.