Abstract:
Maternal allo immunization, occurs when a woman's
immune system is sensitized to foreign erythrocyte
surface
antigens
stimulating
the
production
of
tmmunoglobulin G (IgG) antibodies.
This study was carried out in Khartoum state during the
period from April 2013 to June 2013 to determine of
frequency and type of red blood cells allo-antibodies in
Sudanese multi –parous pregnant ladies attended Bashiaer
University Hospital.
This is a descriptive cross-sectional study. 100 blood
samples were collected from population. Typing of ABO
and Rh (D) blood groups were determine.
Antibodies
screening and identification also were carried out using
tube technique method.
The results showed red blood cells allo-antibodies were
detected in 10 cases (10%). They were anti-Kell was 4
(4%), anti lea was 3 (3%), anti-E was 2 (2%), anti-S was 1
(1%).
The
results
revealed
that
there
was
insignificant
difference between allo-immunization and age, ABO and
Rh, jaundice newborn and number of pregnancies with p
value (0.258, 0.336, 0.481, 0.766) respectively. Significant
relationship was found between allo-immunization and presence of
abortion with p value (0.00).
The study concluded that the determination of red blood
cells allo-antibodies of anti –Kell was the most common.
The relationship of allo-antibodies to many factors such
as , age, ABO and Rh (D) blood group, jaundice newborn
and number of pregnancies was insignificant. There is a
significant relationship between allo-immunization and presence of
abortion.
