Abstract:
In this study, fasting blood glucose level,
microalbuminuria, triglycerides, total cholesterol, and its
lipoprotein fractions HDL and LDL were measured in non-
insulin-dependent diabetic patients.
30 non-insulin-dependent diabetic were grouped as follow :
•
19 NIDDM patients with microalbuminuria.
•
11 NIDDM patients without microalbuminuria were
chosen as control.
In this study, total cholesterol, LDL, triglycerides were
significantly higher in NIDDM patients with microalbuminuria
than in NIDDM patients without microalbuminuria. While HDL
cholesterol was observed to be normal in NIDDM with and
without microalbuminuria.
According to the sex differences, females NIDDM with
microalbuminuria showed increased levels of microalbuminuria,
total cholesterol, triglyceride and LDL which may be due to
obesity and lipid imbalance in females compared to males.
Elevated plasma glucose observed in the two groups (NIDDM
with and without microalbuminuria).
This result revealed that levels of total cholesterol, LDL
cholesterol and triglycerides increased in NIDDM patients with
microalbuminuria, in comparison with NIDDM without
microalbuminuria.
There was no correlation between microalbuminuria and
duration of diabetes. In contrast microalbuminuria correlated
positively with total cholesterol, LDL-cholesterol and
triglyceride, this show the relation between lipid abnormalities
and microalbuminuria and have been thought to play a role in a
therogenesis in diabetes.