Abstract:
This study was carried in Khartoum state during the period from April
2009 to march 2010, to investigate the association between the cervical
cellular changes and microbial infections. One hundred and ten high
vaginal swabs and Papanicolaou smears were collected from patients
attended Um El moamineen charity gynecologic clinic. The swabs were
cultured on blood agar, chocolate blood agar and MaCconkey agar for
primary isolation of the pathogens. Identification of isolates was done by
colonial morphology, Gram's staining technique and biochemical tests.
The cervical smears firstly fixed in 95% ethyl alcohol and then stained
with Pap stain and screened for cell changes or atypia if present.
The study reveled that Bacterial infection were the main cause of
vaginintis followed by Candida species infections, other bacteria were
found also to be source of infection but in varies percentages like
Staphalococuus Auerus, streptococcus species, E.coli, N. gonarrhea and
other types were also isolated. After cytology screening 55.5% showed
normal smear, 40% showed inflammatory cells and infection with
different types (bacterial, fungal, parasitic and some showed non specific
inflammatory changes), 3.6% showed dyskaryosis and only 0.9% showed
invasive squamous cell carcinoma.
The statistic results showed a significant relationship between microbial
infections and cervical cellular changes.
