Abstract:
This study was conducted during the period of May to August 2013
in order to evaluate the concentration of calcium, phosphate and
albumin in blood of CRF patients pre- haemodialysis, 50 CRF
patients under regular dialysis were enrolled in this study in which
they include 30 males and 20females with an ages between (20-
75) years, other 40 apparently healthy and non CRF patient were
also included in this study to serve as control. All participates were
meat Alamal National Hospital
( Khartoum) in which the
clinical assessment were made by physician .
S.P.S.S statistical program was used for the analysis of the data
obtained.
The result of this study showed that the level of calcium and
albumin in the blood of CRF patients were significantly reduced in
comparison with control, being
(8.08 ± 0.63) and (9.28 ±
0.45) mg/dl for calcium in patients with CRF and control respectively
p.value= 0.00 , and albumin (3.03 ± 0.46) and (3.95 ± 0.29) g/dl in
case and control respectively.
But phosphate exhibited significant elevation in CRF patients when
compare with control value being (6.02 ± 1.41) and (3.63 ± 0.36)
mg/dl in case and control respectively, p.value= 0.00.
The result also showed that the three parameters Calcium,
Phosphate and Albumin measured in the blood of male and female
CRF patient were not altered values in male nearly the same as in
female .
The result also showed that the calcium level of CRF patients was
significantly higher in older patient , age between 51- 75 than the
young and middle age patient of age between 20-50 ,
p.value=0.05 , while phosphate and albumin were not affected by
age.
The study also showed that the calcium, phosphate and albumin
were not affected by the duration of CRF.
Pearson correlation analysis showed that no correlation exhibited
between the three parameters calcium, phosphate and albumin
measured in the blood of the CRF patients and the age of patients,
but significant negative correlation was found between calcium and
phosphate.