Abstract:
This is an analytical case-control study was conducted at Al- Ahfad
Family Center during the period from January to April 2010. The aim of
this study was assessment of the haemostatic parameters (platelet, PT and
APTT) in women under administration of combined oral contraceptive
who visited Al- Ahfad Family center. Forty eight women under pills were
enrolled in
after being consented the study and agreed for
participation. The study population was divided into two groups
according to age, first group women above age 30 years and the second
lower 30 years, and tow groups according to duration first group between
3-12 months and second group more than 12months intake.
Five ml of venous blood was bleed 2.5ml in EDTA containers and 2.5 ml
in tri sodium citrate containers and investigated for the platelets count,
PT, APTT tests. Fully automated hematological analyzer Sysmex was
used for platelets count and automated coagulometer Biobas for PT,
APTT.
Women under pills had a mean value of Platelet of 309 .000/cmm. This
value was significant higher than that of control (270.000 /cmm) and with
a P value of 0.039. PT (12.6 second) shorter than control (15.0) with P
value 0.297 and APTT (26.4second) was found within the normal range
and was not different from that of control. This study concluded that
women under combined oral contraceptives were at risk of thrombophilia
due to increased platelets counts.