Abstract:
This study focused on the kidney malfunction in respect to filtration and
excretion, therefore the main objective of this study was to characterize the
GFR disorders by using renal scintigraphy, in order to relate the GFR to
specific renal pathology. This study was conducted at Radiation an Isotopes
Center in Khartoum at the nuclear medicine department, in the period from
Feb 2011 to Jun 2011. The data were collected from 52 patients with renal
problems where 28 patients had non-functioning kidney and 24 had
obstructive kidney.
99m
Tc- DTPA were administered to the patient
intravenously and gamma camera ‘Philips’ was used to detected the count
and hence GFR were calculated. The result showed that the GFR was
linearly associated with the age, weight and height in an inverse fassion for
non function and obstructive kidney group. The coefficient for the non-
function kidney group is equal to 0.64ml/year, 0.3ml/cm, and 0.3ml/Kg for
age, height and weight respectively and for the obstructive one it was
0.22ml/year, 0.09ml/cm, and 0.09ml/Kg respectively. In respect to
maximum uptake for the non-function kidneys group the GFR were decrease
by coefficient equal to -0.5ml/min and 0.2ml/min for the right and left
kidney respectively, while for the obstructive group the GFR increased by a
coefficient equal to 1.4 ml/min and 0.42 ml/min for the right and left kidney
respectively.