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Antimicrobial Resistance of Salmonella typhi Isolated from Patients with Typhoid Fever

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dc.contributor.author KirElseed, Safa Madani Hassan
dc.contributor.author Supervisor, - Humodi Ahmed Saeed
dc.date.accessioned 2013-10-01T09:06:20Z
dc.date.available 2013-10-01T09:06:20Z
dc.date.issued 2012-12-01
dc.identifier.citation KirElseed,Safa Madani Hassan.Antimicrobial Resistance of Salmonella typhi Isolated from Patients with Typhoid Fever/Safa Madani Hassan KirElseed;Humodi Ahmed Saeed.-Khartoum:Sudan University of Science and Technology,Medical Laboratory Science,2012.-50p.:ill.;28cm.-M.Sc. en_US
dc.identifier.uri http://repository.sustech.edu/handle/123456789/1822
dc.description Thesis en_US
dc.description.abstract The objective of this study was to determine the antimicrobial resistance patterns of Salmonella typhi (S. typhi) isolated from patients with typhoid fever. The study was carried out in Khartoum State during the period from March 2012 to October 2012. Stool specimens were collected from patients suffering from typhoid fever who attended Khartoum, Omdurman and Ibrahim malik Teaching hospitals. The specimens were cultured on selenite F broth then Xylose lysine Deoxycholate (XLD) to isolate the causative agent. The identification of the isolates was done by colonial morphology, Gram stain and biochemical tests. Antimicrobial resistance of each isolate was determined by modified Kirby-Bauer disc diffusion method. The antibiotics used were tetracycline, ceftazidime, co-trimoxazole, ciprofloxacin, ceftriaxone and chloramphenicol. Out of 100 stool specimens investigated, only 7 isolates of S. typhi were recovered. Antimicrobial susceptibility test showed that the resistance rate of S. typhi was as follows: 100% to tetracycline and ceftazidime, 50% to co- trimoxazole and no resistance was noticed against ciprofloxacin , ceftariaxone and chloramphnicol. The study concluded that the resistance of S. typhi to tetracycline is very high, but still sensitive to members of quinolone such as ciprofloxacin and ceftriaxone. Further studies with large number of specimens are highly recommended to validate the present study. en_US
dc.description.sponsorship Sudan University of Science and Technology en_US
dc.language.iso en en_US
dc.publisher Sudan University of Science and Technology en_US
dc.subject Sallmonella en_US
dc.subject Typhoid Fever
dc.title Antimicrobial Resistance of Salmonella typhi Isolated from Patients with Typhoid Fever en_US
dc.title.alternative مقاومة مضادات الميكروبات عند السالمونيلة التيفية المعزولة من مرضى الحمى التيفية
dc.type Thesis en_US


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