Abstract:
The level of trace elements, magnesium and zinc were monitored in 80
diabetic patents and in 20 apparently non diabetic subjects in order to study
the impact of diabetes mellitus diseases on the status of these trace elements
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and to discuss the i of the diabetic patents and to discuss the beneficial of
impact the up normality levels of these trace elements on the health of
diabetic patients of the elements to the diabetic patents.
The results obtained were as follows.
Control subjects presented with adequate levels of blood glucose of
a mean of 80 mg/dl, while diabetic patients presented with high level of
blood glucose of amine of 214.25 mg/dl, p values of 0.000 at 0.05 level of
significancy .
Glycosylated sated hemoglobin (Hb A1C) measurements in diabetic
patients, also showed that control group maintained normal percentage of
HbA1C, being 5.310% while diabetic patient showed abnormal high value
11.52% of HbA1C at p value of 0.000 at 0.05 level of significancy. This result
may indicate that the majority of the 80 diabetic patients presented with
poor glycemic control.
The result also indicated that about 61.25% of the diabetic patients were
obese (MBI was more than 30), while 25.75% and 13.75% were lean and
underweight respectively.
The result of this study also indicated that magnesium level in the
dibasic patent was significant reduce compared with control, being 1.285
mg/dl while it was 2.5 mg/dl in control subject a reduction of about 48.6%
was seen at p.value 0.011, at 0.05 level of significancy . Zinc also 60.94
mg\dl and 105.50 mg\dl in control and diabetic patients, a reduction 42.8 %
of control value was obtained, at p value of 0.000, and 0.05 level of
significancy .
The findings of this study also showed that diabetic males nearly maintained
the same levels of magnesium, zinc, and HbA1C as in females , no significant
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differences at 0.05 of significancy seen were observed between the means of
these parameters in male and female.
The levels of trace elements magnesium and zinc were investigated
according to the glycemic control of the diabetic patents. It was found that
magnesium was positively correlated with HbA1C (r = 0.233, p = 0.037) at
0.05 level (2- tailed) and was weakly negatively correlated with blood
glucose (r = -0.235, p = 0.036) at 0.05 level (2- tailed)
Zinc on the other hand, showed no correlation with Hb A1C (r= - 0.005,
p = 0.967), nor with blood glucose (r = - 0.201, p = 0.074) at 0.05 level (2-
tailed).
Trace elements magnesium and zinc showed moderate correlation
between them in the blood of the diabetic patients (r = 0.343, p= 0.002) at
0.05 level (2- tailed).
The results obtained from this study may suggested that
supplementation of magnesium and zinc to diabetic patients may be of great
beneficial effects and can enhance the glaycemic control by reducing
glucose level, decrease percentage of HbA1C and increase insulin sensitivity