Abstract:
Across sectional study conducted during the period
from April to September 2012 . In this study, serum total
cholesterol, high density lipoprotein cholesterol (HDL-c) and
low density lipoprotein cholesterol (LDL-c) were estimated in
90 pregnant women during normal pregnancy (30 in first
trimester, 30 in second trimesters, 30 in third trimesters)
as a test group, and 40 apparently healthy non pregnant
women included as a control group.
The mean of the serum levels of total cholesterol were
significantly increased in the pregnant group when compared
with the control group ( P < 0.05 ). Whereas there was no
significant difference between the means of the serum HDL-c
and LDL-c of the pregnant group when compared with the
control group ( P > 0.05 ).
The comparison between the different trimesters of
pregnancy for serum total cholesterol and LDL-c shows
significant increase, but there is no significant increase for
HDL-c.
The study shows a moderate positive correlation
between the serum levels of total cholesterol and low
density lipoprotein, and duration of pregnancy , and aweak positive correlation between the serum level of high density
.lipoprotein and duration of pregnancy
This study concluded that total cholesterol and low
density lipoprotein are increased in Sudanese pregnant
women, whereas high density lipoprotein is not affected
during pregnancy, and the serum level of total cholesterol
and LDL-c have a moderate positive correlation with the
.duration of pregnancy